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Chronic Obstructive Pulmonary Disease (COPD) Patients Diagnosed With Gastro Esophageal Reflux Disease (GERD). Rates of COPD Exacerbations After Treatment With High Dose Proton Pump Inhibitor Therapy - NCT00523367-32207(Clinical Trial 356488)



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City:  Jacksonville
State:  
FL
Zip Code: 32207
Conditions: Gastroesophageal Reflux - Chronic Obstructive Pulmonary Disease
Purpose: The purpose of this study is to determine which COPD patients have GERD and if COPD patients with GERD treated with high dose lansoprazole for 1 year decreases the frequency of COPD exacerbations compared to the previous year without treatment.
Study summary:
Criteria: Inclusion Criteria: - diagnosis of COPD - forced expiratory volume/forced vital capacity ratio (FEV1/FVC) of < 70% on pulmonary function testing - age > 40 years - >20 pack year history of smoking Exclusion Criteria: - presence of the following disorders: respiratory disorders other than COPD, known esophageal disease such as cancer, achalasia, stricture, active peptic ulcer disease, Zollinger-Ellison syndrome, mastocytosis, scleroderma, or current abuse of alcohol defined as greater than three alcoholic drinks per day.
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Data Source: ClinicalTrials.gov
Date Processed: October 22, 2010
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