| City: |
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Seattle |
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State:
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WA |
| Zip Code: |
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98108 |
| Conditions: |
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Posttraumatic Stress Disorder - Depression |
| Purpose: |
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The present study is a randomized, controlled trial that compares Behavioral Activation
(BA), to Usual VA Care (UC) as early psychotherapeutic interventions for OIF/OEF veterans
with posttraumatic stress disorder (PTSD), or PTSD and major depressive disorder (PTSD/MDD).
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| Study summary: |
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A sizable proportion of soldiers involved in the Iraq and Afghanistan conflicts are
experiencing mental health and adjustment problems on their return, including posttraumatic
stress disorder and depression (Hoge et al., 2004). Both PTSD and depression can be chronic
and debilitating disorders, associated with impairments in social, occupational, and
physical functioning, as well as high health care utilization (Katon, Unutzer, & Simon,
2004; Stein et al., 2005).
Although empirically supported treatments exist for established PTSD and depression, much
less is known about effective early interventions for these conditions. Exploration of
early intervention options is necessary, particularly in the case of the new veteran
population, as such interventions could address social, occupational and physical
impairments before they become too intractable. Also, successful early interventions could
curtail high health care utilization dramatically across time. The development of such
early interventions for PTSD and depression must also take into account any specifications
of accessibility and acceptability that are particular to the OIF/OEF veteran population.
The present study is a randomized, controlled trial that compares Behavioral Activation
(BA), to Usual VA Care (UC) as early interventions for OIF/OEF veterans with posttraumatic
stress disorder (PTSD), or PTSD and major depressive disorder (PTSD/MDD). BA will be
delivered in the primary health care setting (to increase acceptability and accessibility to
the veteran population). Both BA and UC treatment groups will be administered by
psychotherapists who specialize in the treatment of PTSD. Both groups will be assessed at
pre-, mid- and several post-treatment time points to determine maintenance of diagnostic
change over time, health care utilization and treatment satisfaction. This is a dual-site
study that will be carried out at both the Portland VA Medical Center (PVAMC) and the VA
Puget Sound Health Care Center (VA PSHCS) and coordinated at the PVAMC. |
| Criteria: |
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Inclusion Criteria:
1. Ability to comply with assessment and therapy schedule.
2. Ability to comply with study regulations.
3. English fluency.
4. Must meet diagnostic criteria for PTSD (related to trauma experienced during military
service) or PTSD (related to trauma experienced during the military) and major
depressive disorder (MDD). PTSD will be assessed using the Clinician-Administered
PTSD Scale for DSM-IV (CAPS; Blake, Weathers, Nagy, Kaloupek, Charney & Keane, 2003).
Major Depressive Disorder (MDD) will be assessed using the Structured Clinical
Interview for DSM-IV Axis I Disorders (SCID-I; First, Spitzer, Gibbon & Williams,
2002).
Exclusion Criteria:
1. Bipolar disorder.
2. Psychotic disorders.
3. Substance dependence. Because these conditions warrant alternative treatments.
Bipolar, psychotic and substance dependence disorders will be assessed using the
Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I; First, Spitzer,
Gibbon & Williams, 2002).
4. Report active and imminent suicidal intent. If imminent suicidality is present, this
would suggest that a treatment specifically targeting this intent is indicated.
Suicidal intent will be assessed using The Brief Assessment for Suicidal Ideation or
Behavior that was designed for this study. |
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| Study is available at: |
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VA Puget Sound Health Care System, Seattle
Seattle, WA 98108
United States
Primary Contact:
Matthew Jakupcak, PhD
Email: matthew.jakupcak@va.gov
Phone: 206-277-1853
Secondary Contact:
Margaret (Meg) T Kincaid
Email: margaret.kincaid@va.gov
Phone: (503) 220-8262 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 22, 2011 |
Modifications to
this listing: |
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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