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Follicle Stimulating Hormone (FSH) Receptor Polymorphisms in In-Vitro Fertilization Cycles. - NCT01002885-07604(Clinical Trial 385544)



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City:  Hasbrouck Heights
State:  
NJ
Zip Code: 07604
Conditions: Infertility
Purpose: This study is being done to identify if certain sequences (patterns) of key genes (called polymorphisms) may predict a response to fertility medications. The investigators will also determine if the individual response to fertility medications affects pregnancy rates in in-vitro fertilization.
Study summary: All IVF patients who meet inclusion criteria and not exclusion criteria will be asked to participate in this study. Upon consent, a blood sample will be obtained in 2 EDTA containing lavender topped tubes before, during or within 3 months after their IVF cycle. Genomic DNA will be extracted and saved for genotyping. The Investigators will collect data on each individual's age, ethnic background, and estradiol levels on the day of hCG administration, total gonadotropin amount, clinical pregnancy rates, basal FSH levels, and occurrence of OHSS. The Investigators will then analyze all samples from all patients for their FSH receptor genotypes. Patients will be compensated $75 via a check within 6-8 weeks of their blood drawn.
Criteria: Inclusion Criteria: 1. 100 women less than 35 years old at time of signing the Informed Consent Form. 2. Day 3 FSH level less than or equal to 10 mIU/ml with an estradiol < 70 pg/ml 3. Day 3 antral follicle count of greater than 10 follicles total. 4. Couples who have male factor infertility, tubal factor infertility, and unexplained infertility. Exclusion Criteria patients who have: 1. Endometriosis 2. Polycystic ovarian syndrome
Study is available at: University Reproductive Associates
Hasbrouck Heights, NJ 07604
United States

Primary Contact:
Amy Solnica, RN MSN
Email: amysolnica@gmail.com
Phone: 973-972-3633

Secondary Contact:
Amy Solnica, RN, MSN
Email: amysolnica@gmail.com
Phone: 973-972-3633
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 23, 2011
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