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A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Blood Pressure - NCT01005290-(Clinical Trial 386033)



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City:  New York
State:  
NY
Zip Code:
Conditions: Hypertension
Purpose: The purpose of this study is to compare the effect on systolic pressure of the 3 drugs given together in the cardiovascular combination pill (acetylsalicylic acid, simvastatin, and ramipril) to the effect on systolic pressure of ramipril given alone.
Study summary:
Criteria: Inclusion Criteria: - Subjects will be ≥18 years old - Previously untreated systolic pressure result of ≥120<160 mmHg and diastolic pressure result of ≥80<100 mmHg Exclusion Criteria: - Subjects must not have previously received any anti-hypertensive medication - must not have a systolic pressure <120 mmHg or ≥160 mmHg and diastolic pressure result of <80 mmHg or ≥100 mmHg - must not have had a previous coronary artery bypass graft (CABG) - must not have had a previous percutaneous transluminal coronary angioplasty (PTCA) with a drug-eluting stent - must not have severe congestive heart failure (New York Heart Classification [NYHC] III-IV).
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Data Source: ClinicalTrials.gov
Date Processed: February 17, 2011
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