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Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI) - NCT00880555-35233(Clinical Trial 395835)



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City:  Birmingham
State:  
AL
Zip Code: 35233
Conditions: Alzheimer Disease - Dementia
Purpose: Alzheimer's disease often manifests as a memory disorder before dementia develops. Dementia is considered to be present when a person can no longer handle complex activities of daily living, such as managing finances. This study will investigate the relationship between changes in the ability to manage finances and brain perfusion, which will be measured using continuous arterial spin-labeling (an experimental MRI). Subjects will also undergo neuropsychological tests focusing on several types of memory and thought process, with special emphasis on semantic memory. An important question to be addressed is whether changes in function are better predicted by the neuropsychological tests or by the brain scan.
Study summary:
Criteria: Inclusion Criteria: - Veteran - Age 50-89 - With or without memory impairment - English speaking - Right handed - Adequate vision and hearing to take part in tests - Able and willing to undergo MRI scan - Medically and psychiatrically stable - No other brain disease (such as tumor, Parkinson's disease, major stroke) Exclusion Criteria: - Pregnancy - Inability to tolerate MRI (due to metal in body or claustrophobia)
Study is available at: VA Medical Center, Birmingham
Birmingham, AL 35233
United States

Primary Contact:
David G Clark, MD
Email: dgclark@uab.edu
Phone: 205-996-6050

Secondary Contact:
David G Clark, MD
Email: dgclark@uab.edu
Phone: (205) 996-6050
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 23, 2011
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