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A Study Of PF-03463275 As Add-On Therapy In Outpatients With Persistent Negative Symptoms Of Schizophrenia - NCT00977522-20016(Clinical Trial 398230)



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City:  Washington
State:  
DC
Zip Code: 20016
Conditions: Schizophrenia
Purpose: This study is examining the efficacy of PF-03463275 compared to placebo in treating negative symptoms of schizophrenia when added to ongoing antipsychotic treatment in stable outpatients with schizophrenia.
Study summary:
Criteria: Inclusion Criteria: - Subjects must have a current diagnosis of schizophrenia of paranoid (295.30), disorganized (295.10), or undifferentiated (295.90) subtype in the residual phase. - Subjects must be in ongoing maintenance antipsychotic monotherapy with risperidone, olanzapine, quetiapine, ziprasidone, paliperidone, or aripiprazole. Subjects must be on a stable medication treatment regimen for at least 2 months. - Evidence of stable symptomatology at least 3 months. Exclusion Criteria: - Female subjects who are pregnant or breastfeeding. - Subjects with evidence or history of a clinically significant medical condition which would increase risk or which could interfere with the interpretation of trial results. - Subjects who have DSM IV defined psychoactive substance dependence (including alcohol and excluding nicotine and caffeine dependence) within 12 months of screening or substance abuse within 3 months prior to screening.
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Data Source: ClinicalTrials.gov
Date Processed: October 8, 2010
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