A Brief Study To Evaluate The Safety, Tolerability, And Blood Levels Of Multiple Doses Of PF-044467943 Or Placebo In Combination With Donepezil In Subjects With Mild To Moderate Alzheimer's Disease - NCT00988598-91206(Clinical Trial 491541)
ClinicalConnection.com has recently undergone an update and this page may no longer be up-to-date. Please Search For Clinical Trials to view the most current clinical trials listings.
| City: |
|
Glendale |
|
State:
|
|
CA |
| Zip Code: |
|
91206 |
| Conditions: |
|
Alzheimer's Disease |
| Purpose: |
|
The purpose of the study is to evaluate the safety of PF-04447943 when given in combination
with donepezil in subjects who have Alzheimer's Disease. The study will also evaluate the
absorption and distribution of both PF-04447943 and donepezil.
|
| Study summary: |
|
|
| Criteria: |
|
Inclusion Criteria:
- Subjects must have Alzheimer's dementia with a Mini Mental State Examination score
between 18-26, inclusive.
- Subjects must have a reliable caregiver.
- Subjects must be on Aricept
- Memantine is allowed if subjects are on a stable dose
- Subjects must be in reasonably good health, based on medical history, physical
examination, vital signs, and ECG, with no serious or unstable disease within the
past 3 months.
Exclusion Criteria:
- Subjects with clinically significant heart disease cannot participate.
- Subjects with a past or current history of seizures cannot participate. |
|
|
|
|
|
|
|
|
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
|
| Trials Alerts: |
|
If you would like to be
notified of new clinical trials as they become available please
register for a free account.
|
|
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
August 3, 2010 |
Modifications to
this listing: |
|
Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
|
|
|
|
|
|
|
|