Parkinson's Disease - Reseda CA (Clinical Trial # 14165)

This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.
Signup
Browse Studies

City: Reseda
State: CA
Zip Code: 91335
Study summary: It takes a steady hand to manage life with Parkinson’s disease.

If you have been diagnosed with early or advanced stage Parkinson’s disease, you may want to learn more about the TANDEM clinical trials.

The TANDEM trials are evaluating an oral, once-a-day medication to see if it is safe and effective for the treatment of Parkinson’s disease.

Why are these trials taking place?

Most commonly diagnosed in older patients, Parkinson’s disease currently has no cure. Doctors typically prescribe drugs like dopamine and L-dopa to help control some of the symptoms, but these drugs often lose their effectiveness after extended use. Because there is no cure and current treatment options tend to lose effectiveness over time, new treatments for Parkinson’s are needed today.

In the TANDEM trials, doctors want to learn more about a medication called ropinirole prolonged release (PR). Developed for the treatment of early and advanced Parkinson’s disease, ropinirole PR may allow patients to take only one dose a day to treat their condition. This trial may also provide doctors with a better understanding of patient responses to ropinirole PR when it is taken in combination with L-dopa.

Who can participate?

To pre-qualify for a TANDEM trial, you must be:
  • At least 30 years of age
  • Diagnosed with early stage or advanced stage Parkinson’s disease
  • Receiving L-dopa for no more than 3 months prior to the trial (if early stage)
  • Receiving a stable dose of L-dopa for at least 4 weeks prior to the trial, yet still experiencing Parkinson’s disease symptoms (if advanced stage)
There are other eligibility criteria that the study doctor or staff will review with you.

All trial-related visits, tests, and treatments will be provided to participants at no cost. In addition, reimbursement for travel may be provided.

What do the trials involve?

If you choose to participate, you will be asked to:
  • Sign an informed consent document before beginning any study-related activities
  • Attend a screening visit to determine eligibility
  • Have a physical examination, electrocardiogram (ECG), and other study-related tests and assessments
  • Patients with advanced Parkinson’s will also be asked to keep a trial diary over the 3 days immediately before a scheduled clinic visit
If you are eligible and agree to participate, you will be randomly placed into one of six treatment groups.

Five groups will be given ropinirole PR tablets, and one group will receive placebo tablets, which look like ropinirole PR, but contain no active ingredients. You will have a five in six chance of receiving treatment with ropinirole PR.

Depending on the stage of your Parkinson’s disease, trial participation will last between 29 and 33 weeks.

What are the risks and benefits?

Your health and well-being will be monitored during the trial. As with any clinical trial, your Parkinson’s symptoms may or may not improve as a result of your participation. Ropinirole PR has been studied in Parkinson’s patients before and has been shown to be effective in patients with early and late stage Parkinson’s. It is currently approved in the United States, Canada, South Africa, South Korea, Chile, and several European countries.

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials or take the Participation Quiz to find out if you are a good candidate for clinical trial participation.

  • NEARBY STUDIES

    (updated 26 minutes ago)
Within 25 Miles

Sleep Apnea - Santa Monica CA

Cat Allergies - Los Angeles CA

Alzheimer's Disease - Encino CA

Alzheimer's Disease - Los Angeles CA

Alzheimer's Disease - Pasadena CA

Alzheimer's Disease - Simi Valley CA

Early Alzheimer's Disease - Sherman Oaks CA

Early Alzheimer's Disease - Glendale CA

Early Alzheimer's Disease - Simi Valley CA

Alzheimer's Disease/Mild Cognitive Impairment - Glendale CA

Asthma - Los Angeles CA

Sleep Apnea - Los Angeles CA

Sleep Apnea - Santa Monica CA

Healthy Male Volunteers - Glendale CA

Overactive Bladder - Valley Village CA

Mild Cognitive Impairment and Alzheimer's Disease - Glendale CA

Irritable Bowel Syndrome with Constipation - Canoga Park CA

Pediatric Depression - Culver City CA

Pediatric Depression - Glendale CA

Alzheimer's Disease - Valley Village CA

Memory Loss - Sherman Oaks CA

Smoking Cessation - Los Angeles CA

Coronary Artery Disease - Northridge CA

High Triglycerides - Northridge CA

Heart Failure - Northridge CA

Fibromyalgia - Los Angeles CA

Mental Health - Los Angeles CA

Early Alzheimer's Disease - Sherman Oaks CA

Memory Loss - Sherman Oaks CA

Diabetes Type 2 - Los Angeles CA

Type 1 Diabetes - Los Angeles CA

Type 1 Diabetes - Los Angeles CA

Type 2 Diabetes - Los Angeles CA

Smokers (African American/Black) - Los Angeles CA

Early Alzheimer - Los Angeles CA

Type 2 Diabetes - Canoga Park CA

Type 2 Diabetes (Mellitus) - Canoga Park CA

Alcohol Use Disorder - Los Angeles CA

Asthma - Canoga Park CA

High Cholesterol - Valley Village CA

Knee Pain or Hip Pain - Valley Village CA

Osteoarthritis - Valley Village CA

Osteoarthritis of the Knee - Santa Monica CA

Irritable Bowel Syndrome with Constipation (IBS-C) - Northridge CA

Osteoarthritis - Canoga Park CA

Bunion - Pasadena CA

Diabetes Mellitus (Type 2) - Los Angeles CA

Diabetes Type 2 - Los Angeles CA

Diabetic Foot Ulcers - Los Angeles CA

High Cholesterol - Los Angeles CA

Male Pattern Baldness - Los Angeles CA

Moderate to Severe Acne - Los Angeles CA

Osteoarthritis - Beverly Hills CA

Healthy Volunteers - Gardena CA

Healthy Volunteers - Pasadena CA

Healthy Volunteers (ages 65-85) - Glendale CA

Healthy Volunteers - Glendale CA

Healthy Non-Childbearing Female Volunteers - Glendale CA

Lactose Intolerance - Los Angeles CA

Healthy Elderly Volunteers (ages 70-85) - Glendale CA

Tummy Tuck Surgery - Pasadena CA

Post Shingles Pain - Thousand Oaks CA

Osteoarthritis - Canoga Park CA

Smoking Cessation - Los Angeles CA

Diabetes (Type 2) - Northridge CA

Healthy Volunteers - Glendale CA

Within 50 Miles

Narcolepsy - Orange CA

Sleep Apnea - Orange CA

Sleep Apnea - Orange CA

Alzheimer's Disease - Costa Mesa CA

Alzheimer's Disease - Fullerton CA

Alzheimer's Disease - Long Beach CA

Early Alzheimer's Disease - Fullerton CA

Pediatric Allergies - Costa Mesa CA

Sarcopenia - Costa Mesa CA

Pediatric Depression - Bellflower CA

Pediatric Depression - Costa Mesa CA

Pediatric Depression - Anaheim CA

Pediatric Depression - Anaheim CA

COPD - Lakewood CA

Treatment Resistant Depression - Upland CA

Mild Cognitive Impairment (MCI) - Los Alamitos CA

Depression - Los Alamitos CA

Chronic Obstructive Pulmonary Disorder (COPD, Emphysema) - San Gabriel CA

Migraine - Los Alamitos CA

Osteoarthritis of Knee - Anaheim CA

Skin Infection - Anaheim CA

Smoking Cessation - Los Alamitos CA

Tardive Dyskinesia - Torrance CA

Chronic Migraine - Long Beach CA

Multiple Sclerosis - Long Beach CA

Depression - Garden Grove CA

ADHD - Garden Grove CA

Schizophrenia with Alcohol Use Disorder (AUD) - Garden Grove CA

Parkinson's Disease - Long Beach CA

Post-Stroke - Long Beach CA

Asthma - Long Beach CA

Alzheimer's Disease - Long Beach CA

Osteoarthritis of Knee or Hip - Anaheim CA

Binge Eating - Garden Grove CA

Type 2 Diabetes - Long Beach CA

Early-Onset Schizophrenia - Garden Grove CA

Osteoarthritis - Anaheim CA

Osteoarthritis - Whittier CA

Osteoarthritis - Chino CA

Low Back Pain - Garden Grove CA

Bipolar Depression - Garden Grove CA

Osteoarthritis - Long Beach CA

Type II Diabetes - Long Beach CA

Skin Infection/Wound - Long Beach CA

Schizophrenia - Garden Grove CA

Depression - Garden Grove CA

Schizophrenia - Garden Grove CA

Major Depressive Disorder - Garden Grove CA

Type 2 Diabetes and a History of Heart Disease - Lomita CA

Diabetes Non-insulin Dependent - Orange CA

Obstructive Sleep Apnea with Daytime Sleepiness - Orange CA

Rheumatoid Arthritis - Upland CA

Osteoarthritis of the hip or knee - Huntington Beach CA

Eczema - Lomita CA

Migraines - Los Alamitos CA

Non-Small Cell Lung Cancer (NSCLC) - Duarte CA

Chronic Obstructive Pulmonary Disorder (COPD, Emphysema) - Torrance CA

Schizophrenia - Garden Grove CA

Schizophrenia - Garden Grove CA

COPD - Lomita CA

Osteoarthitis Knee Pain - Long Beach CA

Rheumatoid Arthritis - Huntington Beach CA

Irritable Bowel Syndrome (IBS-C) - Lomita CA

Osteoarthritis - Huntington Beach CA

Osteoarthritis - Orange CA

Tourette Syndrome - Upland CA

Osteoarthitis Knee Pain - Upland CA

Flu - Upland CA

Insomnia, Sleep Apnea or Narcolepsy - Upland CA

Osteoarthritis - Bellflower CA

Lung Cancer - Whittier CA

Lung Cancer - Torrance CA

Lung Cancer - Los Angeles CA

Migraines - Anaheim CA

Mild to Moderate Alzheimer's Disease - Bellflower CA

Mild to Moderate Alzheimer's Disease - Lomita CA

Mild to Moderate Alzheimer's Disease - Carson CA

Mild to Moderate Alzheimer's Disease - Costa Mesa CA

Mild to Moderate Alzheimer's Disease - Santa Ana CA

Mild to Moderate Alzheimer's Disease - Anaheim CA

Mild to Moderate Alzheimer's Disease - Fullerton CA

Mild to Moderate Alzheimer's Disease - Costa Mesa CA

Within 100 Miles

Narcolepsy - Oceanside CA

Sleep Apnea - Oceanside CA

Sleep Apnea - Oceanside CA

Alzheimer's Disease - Santa Ana CA

Alzheimer's Disease - Temecula CA

Early Alzheimer's Disease - Laguna Hills CA

Early Alzheimer's Disease - Oceanside CA

Early Alzheimer's Disease - Redlands CA

Early Alzheimer's Disease - Santa Ana CA

Sleep Apnea - Oceanside CA

Diabetes - Tustin CA

Pediatric Depression - Riverside CA

Pediatric Depression - Irvine CA

Gout - Tustin CA

Blood Glucose Measurement - Irvine CA

Smoking Cessation (Teens Ages 12 through 16) - Oceanside CA

Healthy Volunteers - Tustin CA

Mild Cognitive Impairment (MCI) - Newport Beach CA

Major Depressive Disorder - Redlands CA

Multiple Sclerosis - Newport Beach CA

Type 2 Diabetes (African American) - Tustin CA

ACNE - Tustin CA

Chronic Obstructive Pulmonary Disorder (COPD) - Tustin CA

Migraine - Newport Beach CA

Migraine Headaches - Redlands CA

Asthma in Children - Mission Viejo CA

Smoking Cessation - Newport Beach CA

Fibromyalgia - Tustin CA

Type 2 Diabetes - Laguna Hills CA

Diabetes Type 1 - Tustin CA

Diabetes Type 2 - Tustin CA

Depression - Newport Beach CA

Acne - Tustin CA

Flu - Tustin CA

High Blood Pressure - Tustin CA

Migraines - Irvine CA

Migraines - Redlands CA

Migraines - Newport Beach CA

Rheumatoid Arthritis - Hemet CA

Type 1 Diabetes - Tustin CA

ACNE - Tustin CA

Heart Failure with Kidney Disease - Tustin CA

Healthy Volunteers (Underweight Seniors) - Tustin CA

Binge Eating Disorder - Newport Beach CA

Migraines - Oceanside CA

Osteoarthritis - Oceanside CA

Osteoarthritis - Santa Ana CA

Acne - Oceanside CA

High Blood Pressure - Tustin CA

Cardiovascular Disease (CVD) - Laguna Hills

Post Shingles Pain - Colton CA

Migraines - Apple Valley CA

Mild to Moderate Alzheimer's Disease - Oceanside CA

Type 1 Diabetes - Laguna Hills CA