Emphysema/COPD (Chronic Obstructive Pulmonary Disease) - Philadelphia PA (Clinical Trial # 15919)

This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.
Signup
Browse Studies

City: Philadelphia
State: PA
Zip Code: 19140
Study summary: Study 9968 Flyer
Click image to enlarge

You might be able to help us with the EMPHASIS clinical research study. If you or someone you know:
  • Has emphysema/COPD
  • Is between ages 40 and 75

People taking part in the study will receive study-related health care at no cost.

We hope the EMPHASIS study will help us discover whether the investigational medication has any effect on the breathing of people with emphysema, on how efficiently their lungs work and on other effects of the disease, such as coughing.

Inclusion Criteria:
  • Be male or female, 40-75 yrs old, inclusive
  • Rating of greater than or equal to 1 on the Goddard scale in assessment of emphysema severity by HRCT
  • At least 1 documented COPD exacerbation within the past year but not within 8 weeks of study randomization
  • Current or former smokers with a cigarette smoking history of at least 20 pack-years (or equivalent) and whose smoking status has not changed 60 days prior to screening Exclusion Criteria
  • Patients with asthma, active tuberculosis or bronchiectasis
  • A respiratory tract infection within 30 days prior to the screening visit
  • Any malignancy within 30 days prior to the screening visit
  • Any malignancy within the last 5 years with the exception of non-melanomatous skin cancer
  • Uncontrolled cardiovascular, endocrine, blood or nervous system disorders
  • Uncontrolled condition with COPD exacerbation of level 2 or 3 in the 8-week period prior to randomization
  • Systemic use of corticosteroids or other immunosuppressive agents within 30 days of the screening visit
  • Subjects taking anticoagulants
 

Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials or take the Participation Quiz to find out if you are a good candidate for clinical trial participation.

  • NEARBY STUDIES

    (updated 52 minutes ago)
Within 25 Miles

Endometriosis - Stratford NJ

Endometriosis - Levittown PA

Endometriosis - Philadelphia PA

Obsessive Compulsive Disorder (OCD) - Norristown PA

Obsessive Compulsive Disorder (OCD) - Norristown PA

Memory Loss - Norristown PA

Adolescent Major Depression (Ages 12-17) - Cherry Hill NJ

Adolescent Depression - Cherry Hill NJ

Bipolar Disorder - Cherry Hill NJ

Post-Traumatic Stress Disorder (PTSD) - Norristown PA

Multiple Sclerosis - Philadelphia PA

Attention Deficit Hyperactivity Disorder (ADHD) - Cherry Hill NJ

Osteoarthritis of the Knee - Trenton NJ

Type 1 Diabetes - Jenkintown PA

Depression - Cherry Hill NJ

High Cholesterol - Levittown PA

High Cholesterol - Philadelphia PA

High Cholesterol - Harleysville PA

High Cholesterol - Trenton NJ

High Cholesterol - Lansdale PA

Type II Diabetes - Trenton NJ

COPD (Emphysema and Chronic Bronchitis) - Marlton NJ

Polycystic Kidney Disease (PKD) - Autosomal Dominant (ADPKD) - Doylestown PA

Within 50 Miles

Lupus - Reading PA

Endometriosis - Newark DE

Type 2 Diabetes - Toms River NJ

Atrophic Vaginitis - Plainsboro NJ

Type 1 Diabetes - Trenton NJ

Diabetic Gastroparesis - Vineland NJ

Bacterial Vaginosis - Plainsboro NJ

Anemia - Plainsboro NJ

High Cholesterol - Downingtown PA

Polycystic Kidney Disease (PKD) - Autosomal Dominant (ADPKD) - Bethlehem PA

Within 100 Miles

Type 2 Diabetes - Baltimore MD

Endometriosis - New York NY

Endometriosis - New York NY

Endometriosis - Hershey PA

Gout - New York NY

Multiple Sclerosis (Relapsing) - Dover DE

Depression - New York NY

Adolescent Major Depression (Ages 12-17) - Baltimore MD

Diabetes - New York NY

Obsessive Compulsive Disorder (OCD) - New York NY

Heart Failure After Heart Attack - New York NY

Heart Failure After Heart Attack - New York NY

Heart Failure After Heart Attack - Lemoyne PA

Alzheimer's Disease - Baltimore MD

Temporomandibular Disorder (TMJD) - Baltimore MD

Postherpetic Neuralgia - New York NY

Heart Failure After Heart Attack - Morristown NJ

Social Anxiety Disorder - New York NY

Depression - New York NY

Adult ADHD - New York NY

Depression - New York NY

Healthy Volunteers (Age 18-50) - Baltimore MD

Chronic Obstructive Pulmonary Disease (COPD) - New York NY

Diabetic Nephropathy (Kidney Disease) - New York NY

Healthy Volunteers (Age 18-50) - Baltimore MD

Major Depression Disorder - New York NY

PBA - Pseudobulbar Affect - New York NY

Obsessive Compulsive Disorder (OCD) - New York NY

Healthy Volunteers (Age 18-55) - Baltimore MD

Healthy Volunteers (Age 18-45) - Baltimore MD

Allergies - Baltimore MD

Gout - Lodi NJ

Healthy Volunteers (Age 18-65) - Baltimore MD

Parkinson's Disease - New York NY

Healthy Volunteers (Age 18-60) - Baltimore MD

Healthy Volunteers (Age 18-49) - Baltimore MD

Healthy Volunteers (Age 25-40) - Baltimore MD

Healthy Male Volunteers (Age 18-65) - Baltimore MD

Type 2 Diabetes - Rosedale NY

Type 2 Diabetes - Towson MD

Type 2 Diabetes - Lodi NJ

Type 2 Diabetes - Brooklyn NY

Type 2 Diabetes - Staten Island NY

Fibromyalgia Pain - New York NY

Attention Deficit Hyperactivity Disorder (ADHD) - New York NY

High Cholesterol - Linden NJ

Asthma - Asbury Park NJ

Ankle Sprain - Towson MD

Healthy Volunteers (Age 18-60) - Baltimore MD

Polycystic Kidney Disease (PKD) - Autosomal Dominant (ADPKD) - New York NY

Healthy Female Volunteers (Age 50-65) - Baltimore MD

Healthy Volunteers (Age 18-65) - Baltimore MD

Healthy Male Volunteers (Age 18-56) - Baltimore MD

Healthy Female Volunteers (Age 18-56) - Baltimore MD

Eczema - Baltimore MD

Healthy Volunteers (Age 50-80) - Baltimore MD

High Cholesterol - Brooklyn NY

Endometriosis - Staten Island NY

Asthma in Children (Ages 5-11) - Verona NJ

Asthma in Children (Ages 5 - Asbury Park NJ

Asthma - Edison NJ

Asthma - Baltimore MD

Asthma - Ocean NJ

Alzheimer's Disease - New York NY

COPD (Emphysema and Chronic Bronchitis) - Towson MD

COPD (Emphysema and Chronic Bronchitis) - Bronx NY

Asthma in Children (Ages 5-11) - Neptune NJ

Polycystic Kidney Disease (PKD) - Autosomal Dominant (ADPKD) - Jamaica NY