Scintigraphic Assessment of I- Transport in Metastatic Breast Cancer and Evaluation of I31I Ablative Therapy: (Part I) Radioiodide Imaging Study

Purpose:

The purpose of this study is to examine breast cancers that express the protein (NIS) that may be found in malignant breast tissues and to evaluate proteins found in blood and their relationship to NIS, to test whether iodide can be concentrated by breast cells to possibly treat some breast cancers with radioactive iodine, and to calculate the amount of radioactive iodine entering breast cancer cells, how long your cancer retains the agent as well as how much is taken up by other organs, particularly the thyroid gland.

Study summary:

To demonstrate iodide uptake capacity of breast cancer metastases by imaging women with iodide radioisotope (123I) and calculating potential ablative dose of radioactive iodide (131I).

Criteria:

Inclusion Criteria:- Only women diagnosed with breast cancer - 18 years of age or older - From whom informed consent can be obtained - Patient is able to provide a fluid (e.g. cyst fluid) - Patient with blood test that shows protein may allow iodide to accumulate in breast tissue - Patient who's breast cancer cells accumulated I123 and held on to it for 24 hours Exclusion Criteria:- Males - Children

Study is Available At:

Original ID:

BRSMTS0002

NCT ID:

NCT00185809

Secondary ID:

75632

Study Acronym:

Brief Title:

Scintigraphic Assessment of I- Transport in Metastatic Breast Cancer and Evaluation of I31I Ablative Therapy: (Part I) Radioiodide Imaging Study

Official Title:

Scintigraphic Assessment of I- Transport in Metastatic Breast Cancer and Evaluation of I31I Ablative Therapy: (Part I) Radioiodide Imaging Study

ClinicalTrials.gov Link:

http://clinicaltrials.gov/show/NCT00185809

Overall Status:

Completed

Study Phase:

N/A

Genders:

Female

Minimum Age:

18 Years

Maximum Age:

70 Years

Study Source:

Stanford University

Oversight Authority:

United States: Institutional Review Board

Reasons Why Stopped:

Study Type:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: P

Number of Arms:

0

Number of Groups:

1

Total Enrollment:

25

Enrollment Type:

Anticipated

Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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