Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Charlottesville, Virginia 22908


The purpose of this study is to determine if contrast enhanced ultrasound (CEU) using microbubbles, is useful in assessing changes in kidney blood flow.


Inclusion Criteria: - Healthy adults - Males and females - Ages 18-65 years old Exclusion Criteria: - Pregnancy or lactation - H/o kidney disease - H/o congestive heart failure, ischemic heart disease, severe pulmonary disease or allergy to the drug - H/o any cardiovascular disease - Abnormal liver function (liver function tests out of specified ranges) - Screening urinalysis which indicates infection or inflammation - Taking regular medications (except for over-the-counter vitamins or hormonal contraceptives.) - Taking supplements, like protein shakes - Unwilling or unable to eat chicken (used as protein meal)

Study is Available At:

Original ID:




Secondary ID:

Study Acronym:

Brief Title:

Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound

Official Title:

Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound

Overall Status:


Study Phase:




Minimum Age:

18 Years

Maximum Age:

65 Years

Quick Facts

Healthy Volunteers
Oversight Has DMC
Study Is FDA Regulated
Study Is Section 801
Has Expanded Access

Study Source:

University of Virginia

Oversight Authority:

United States: Food and Drug Administration

Reasons Why Stopped:

Study Type:


Study Design:

Endpoint Classification: Efficacy Study, Interven

Number of Arms:


Number of Groups:


Total Enrollment:


Enrollment Type:


Overall Contact Information

Official Name:Kambiz Kalantarinia, MD
Principal Investigator
University of Virginia
Primary Contact:Kambiz Kalantarinia, MD
434 924 5125
Backup Contact:Lori Ratliff, RN ANP
434 924 5820 ext. 4-1572
434 924 5820

Study Dates

Start Date:June 2006
Completion Date:December 2009
Completion Type:Anticipated
Verification Date:August 2008
Last Changed Date:August 6, 2008
First Received Date:February 27, 2008

Study Outcomes

There are no available Study Outcomes

Study Interventions

Intervention Type:Drug
Name:perflutren lipid microspheres
Description:1.3 ml in 30 ml of saline, infused into vein at 2ml / min and titrated for optimal image quality (not to exceed 10 ml/ min at any time).
Other Name:Definity

Study Arms

There are no available Study Arms

Study Agencies

Agency Class:Other
Agency Type:Lead Sponsor
Agency Name:University of Virginia
Agency Class:NIH
Agency Type:Collaborator
Agency Name:National Institutes of Health (NIH)

Sample and Retention Information

There are no available Sample and Retention Information

Study References

There are no available Study References

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

This study is not currently recruiting Study Participants. The form below is not enabled.