New Haven, Connecticut 06517

  • Social Transmission of Health Behaviors

Purpose:

This project will examine the spread of health interventions with a randomized control trial design by introducing public health interventions in 32 villages in the Honduran Department of Lempira. Based on identified public health needs in the region, namely improved drinking water and diet, this study will provide training on the use of chlorine (sodium hypochlorite) for water purification and multivitamins for nutritional supplementation. In some villages, individuals selected for their social connectedness will be trained and given coupons that can be redeemed for either chlorine bleach or multivitamins, and these persons will be asked to spread this information and distribute coupons to four people of their choosing. In other villages, individuals selected at random will receive the same training, materials, and instructions. A second wave of coupon distribution will provide coupons to those who received a coupon from the original "seed" groups so that they may disperse these coupons further out in the social networks. Over the following months, study investigators will look at how knowledge of these health practices, and uptake or and adherence to the practices, spreads throughout the villages. More specifically, the investigators will examine the speed and extent of spreading of these new health practices after introducing them to three different initial "seed" groups: (1) people chosen on the basis of being named as a friend by many people in their village, (2) people chosen based on being named as a friend by a randomly chosen individual, and (3) a group of randomly chosen individuals. It is hypothesized that spread will occur faster and/or to a greater extent when the intervention is started in groups 1 and 2 versus group 3 (control group).


Criteria:

Inclusion Criteria: - Residents of Targeted Communities, ages 15 and up Exclusion Criteria: - Children younger than age 15


Study is Available At:


Original ID:

Lempira_Phase2


NCT ID:

NCT01672580


Secondary ID:


Study Acronym:


Brief Title:

Social Network Interventions in Rural Honduras


Official Title:

Diffusion of Health Interventions Across Social Networks in Honduran Villages


Overall Status:

Completed


Study Phase:

N/A


Genders:

Both


Minimum Age:

15 Years


Maximum Age:

N/A


Quick Facts

Healthy Volunteers
Oversight Has DMC
Study Is FDA Regulated
Study Is Section 801
Has Expanded Access

Study Source:

Harvard University


Oversight Authority:

Honduras: Ministry of Health


Reasons Why Stopped:


Study Type:

Interventional


Study Design:

Allocation: Randomized, Intervention Model: Factor


Number of Arms:

6


Number of Groups:

0


Total Enrollment:

5773


Enrollment Type:

Actual


Overall Contact Information

Official Name:Nicholas A Christakis, MD, PhD
Principal Investigator
Yale University

Study Dates

Start Date:August 2012
Completion Date:October 2014
Completion Type:Actual
Primary Completion Date:October 2013
Primary Completion Type:Actual
Verification Date:March 2015
Last Changed Date:March 18, 2015
First Received Date:August 20, 2012

Study Outcomes

Outcome Type:Primary Outcome
Measure:Intervention Spread
Time Frame:October 2012
Safety Issues:False
Description:Use of health product among community members will be tracked.

Study Interventions

Intervention Type:Behavioral
Name:nominated by random
Description:"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual
Arm Name:Nominated-Cloro
Intervention Type:Behavioral
Name:high in-degree
Description:"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree
Arm Name:Indegree-Cloro
Intervention Type:Behavioral
Name:exposure to water chlorination
Description:"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village
Arm Name:Random-Cloro
Other Name:Clorox
Intervention Type:Behavioral
Name:exposure to vitamin use
Description:"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village
Arm Name:Random-Vitamin
Other Name:Medox Forte

Study Arms

Study Arm Type:Experimental
Arm Name:Nominated-Vitamin
Description:nominated by random, exposure to vitamin use
Study Arm Type:Experimental
Arm Name:Nominated-Cloro
Description:nominated by random, exposure to water chlorination
Study Arm Type:Experimental
Arm Name:Indegree-Vitamin
Description:high in-degree, exposure to vitamin use
Study Arm Type:Experimental
Arm Name:Indegree-Cloro
Description:high in-degree, exposure to water chlorination
Study Arm Type:Active Comparator
Arm Name:Random-Vitamin
Description:exposure to vitamin use
Study Arm Type:Active Comparator
Arm Name:Random-Cloro
Description:exposure to water chlorination

Study Agencies

Agency Class:Other
Agency Type:Lead Sponsor
Agency Name:Harvard University
Agency Class:Other
Agency Type:Collaborator
Agency Name:Yale University

Sample and Retention Information

There are no available Sample and Retention Information

Study References

There are no available Study References

Data Source: ClinicalTrials.gov

Date Processed: July 29, 2021

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