Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

San Francisco, California 94105


The purpose of this study is to measure the efficacy of an online cognitive training program against an active control condition in a large, randomized trial.

Study summary:

The present study aims to evaluate a targeted, progressively challenging, online cognitive training program comprised of 49 distinct exercises targeting a variety of cognitive capacities. The cognitive training program will be compared to a plausibly beneficial active control condition in which participants completed online crossword puzzles. The investigators hypothesize that the cognitive training will show greater transfer to a range of underlying cognitive abilities than the active control, as measured by a broad battery of neuropsychological assessments and participant-reported outcomes.


Inclusion Criteria: - Engaged with the Lumosity program at least 3 days in the first week after sign-up - Access to an internet enabled computer to complete training Exclusion Criteria: - Paying subscriber

Study is Available At:

Original ID:




Secondary ID:

Study Acronym:

Brief Title:

Enhancing Cognitive Abilities With Comprehensive Training

Official Title:

Enhancing Cognitive Abilities With Comprehensive Training: A Large, Online, Randomized, Active-Controlled Trial

Overall Status:


Study Phase:




Minimum Age:

18 Years

Maximum Age:

80 Years

Quick Facts

Healthy Volunteers
Oversight Has DMC
Study Is FDA Regulated
Study Is Section 801
Has Expanded Access

Study Source:

Lumos Labs, Inc.

Oversight Authority:

United States: Institutional Review Board

Reasons Why Stopped:

Study Type:


Study Design:

Allocation: Randomized, Endpoint Classification: E

Number of Arms:


Number of Groups:


Total Enrollment:


Enrollment Type:


Overall Contact Information

Official Name:Joe Hardy, PhD
Principal Investigator
Lumos Labs, Inc.

Study Dates

Start Date:April 2013
Completion Date:April 2014
Completion Type:Actual
Primary Completion Date:April 2014
Primary Completion Type:Actual
Verification Date:February 2015
Last Changed Date:April 7, 2015
First Received Date:February 13, 2015

Study Outcomes

Outcome Type:Secondary Outcome
Measure:Individual Neuropsychological Assessments composite
Time Frame:Baseline to 10 weeks
Safety Issues:False
Description:Separate analyses of changes on each of the seven neuropsychological assessments in the battery (Forward Memory Span, Reverse Memory Span, Grammatical Reasoning, Progressive Matrices, Go/No-Go, Arithmetic Reasoning, Two-Target Search).
Outcome Type:Secondary Outcome
Measure:Participant-Reported Outcomes
Time Frame:Baseline to 10 weeks
Safety Issues:False
Description:9 questions related to everyday cognition and emotional status.
Outcome Type:Primary Outcome
Measure:Aggregate Cognitive Performance
Time Frame:Baseline to 10 weeks
Safety Issues:False
Description:Aggregate cognitive performance, as measured by Grand Index, on seven neuropsychological assessments (Forward Memory Span, Reverse Memory Span, Grammatical Reasoning, Progressive Matrices, Go/No-Go, Arithmetic Reasoning, Two-Target Search)

Study Interventions

Intervention Type:Other
Name:Lumosity Cognitive Training
Description:adaptive online cognitive training
Arm Name:Cognitive Training
Intervention Type:Other
Name:Crossword Puzzles
Description:timed online crossword puzzles
Arm Name:Crossword Puzzles

Study Arms

Study Arm Type:Active Comparator
Arm Name:Crossword Puzzles
Description:Timed online crossword puzzles
Study Arm Type:Experimental
Arm Name:Cognitive Training
Description:Lumosity cognitive training program.

Study Agencies

Agency Class:Industry
Agency Type:Lead Sponsor
Agency Name:Lumos Labs, Inc.
Agency Class:Other
Agency Type:Collaborator
Agency Name:Wheaton College

Sample and Retention Information

There are no available Sample and Retention Information

Study References

There are no available Study References

Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

This study is not currently recruiting Study Participants. The form below is not enabled.