Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Charleston, South Carolina 29425


This study will investigate the use of sertraline (Zoloft) to decrease alcohol consumption and crime-related post-traumatic stress disorder in those individuals with both disorders. This will be a 12-week, placebo-controlled, double-blind outpatient trial. All subjects will receive cognitive behavioral therapy in addition to a placebo or sertraline. Comprehensive evaluation will be done at study entry; treatment termination; and 6, 9, and 12 months after study entry.


Inclusion Criteria: - Meets criteria for alcohol abuse or dependence and post-traumatic stress disorder. - Laboratory tests for blood and urinalysis must be within normal limits. - Must be clearly motivated to obtain benefit from treatment and keep appointments for study visits and therapy sessions. - Females who use an acceptable method of birth control, are sterilized, or are at least 2 years post-menopausal. Exclusion Criteria: - Have a diagnosis of schizophrenia, bipolar affective disorder, dissociative identity disorder, eating disorder, substance dependence in the last 60 days. - Currently suicidal. - Medical reasons not to receive drug therapy. - Allergy or hypersensitivity to selective serotonin inhibitor antidepressants. - Significant hematological, endocrine, cardiovascular, renal, hepatic, neurological, or gastrointestinal disease. - Liver function test greater than 2 times the normal level - Require ongoing therapy with another psychoactive drug during the study period. - Females who are pregnant or lactating.



Primary Contact:


Backup Contact:


Location Contact:

Charleston, South Carolina 29425
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: December 02, 2018

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.