Expired Study
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Providence, Rhode Island 02912


The study's purpose is to improve alcoholism treatment by investigating the combined effectiveness of a psychotherapy (Coping Skills Training and Cue Exposure Treatment - CSTCET) with naltrexone in a randomized clinical trial. Individuals will receive 2 weeks of CSTCET or a control treatment as inpatients followed by 12 consecutive weeks of receiving either naltrexone or placebo as outpatients. Followups at 24, 48, and 72 weeks after treatment is completed.


Inclusion Criteria: - Meets criteria for alcohol dependence. Exclusion Criteria: - Current diagnosis of dependence on other substances except nicotine. - A history of psychosis or current psychotic symptoms. - Current suicidality, homocidality, or psychiatric symptoms that require additional medication. - Current use of disulfiram (Antabuse). - Evidence of significant cerebral, renal, thyroid, or cardiac disease. - History of opioid abuse in the previous year. - History of cirrhosis, hepatocellular disease, or elevated bilirubin. - Females who are pregnant, nursing, or not using a reliable method of birth control.



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Providence, Rhode Island 02912
United States

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Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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