You are viewing an expired study

This study is not currently recruiting Study Participants on If you would like to find active studies please browse nearby listings below.

Click here to view additional nearby studies or search for clinical trials.

Duluth, Minnesota 55805

  • Colorectal Cancer


RATIONALE: Genetic studies may help in understanding the genetic processes that cause some types of cancer. PURPOSE: Genetic trial to study certain genes of patients who have stage II or stage III colon cancer.

Study summary:

OBJECTIVES: - Determine the adverse prognostic significance of 8p allelic imbalance (AI) in patients with colon cancer. - Determine if patient prognosis is dependent on the region of 8p AI. - Perform fine mapping studies to further localize the putative tumor suppressor gene(s) on 8p. - Perform multicolor FISH to examine the role that 8p loss and 8q gain play in the prognosis of patients whose tumors exhibit 8p AI. OUTLINE: Matched normal and tumor DNA is analyzed for 8p allelic imbalance with at least 8 markers: D8S262 and D8S1825 localized to 8p23, D8S254 and D8S261 at 8p22, D8S560 and D8S136 at 8p21, and D8S1820 and D8S283 at 8p12. Normal/tumor tissue pairs are used for fine mapping studies.


DISEASE CHARACTERISTICS: - Diagnosis of resectable stage II or III adenocarcinoma of the colon - Participated in NCCTG-914653 - DNA extracted from both normal and tumor tissue PATIENT CHARACTERISTICS: Age - Under 70



Primary Contact:

Study Chair
Richard M. Goldberg, MD
Mayo Clinic

Backup Contact:


Location Contact:

Duluth, Minnesota 55805
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source:

Date Processed: April 07, 2020

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on The form below is not enabled.