Miami, Florida 33133

  • HIV Infections


The purpose of this study is to look at the safety and effectiveness of dextrin sulfate in AIDS patients who have failed conventional anti-HIV treatment.

Study summary:

Patients have intraperitoneal (IP) catheter placement done at study entry. Infusion with the carrier vehicle (icodextrin 4%) begins 2 weeks later, and 2 days after that, treatment with dextrin sulphate (DS) commences. DS is given three times per week. A nurse delivers initial treatments and the patient and caregiver will be trained to give subsequent treatments until DS has been given a total of 8 weeks. Patient evaluations are done regularly during treatment and observation continues for 24 weeks.


Inclusion Criteria Patients may be eligible for this trial if they: - Are HIV-positive. - Have been diagnosed with AIDS and are under treatment to prevent opportunistic (AIDS-related) infection. - Have had a CD4 cell count greater than 50 microL for at least the past 3 months. - Have had a viral load of at least 50,000 copies/ml for at least the past 3 months. - Have used up all other treatment options. - Are able to understand and give written consent. Exclusion Criteria Patients may not be eligible for this trial if they: - Have been in any other study in the 6 weeks before beginning this study. - Have an active, opportunistic infection or other infection. - Have any other long-term medical condition or nervous disorder that might make it difficult for them to finish the study.



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Location Contact:

Miami, Florida 33133
United States

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Site Status: N/A

Data Source:

Date Processed: June 21, 2021

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