Expired Study
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Ft. Lauderdale, Florida 33316


The purpose of this study is to study the safety and efficacy of Amprenavir/ritonavir or saquinavir/ritonavir in HIV infected patients that have failed Kaletra as their second protease inhibitor based HAART.


Inclusion: - Subject must remain on current antiretroviral therapy during screening until a new regimen is initiated. - Subject demonstrates reduced susceptibility to lopinavir. - Subject's two most recent viral loads obtained after at least 16 weeks of lopinavir/ritonavir therapy, and while still on Kaletra therapy must be at least 1,000 copies/mL. - The Kaletra regimen must be the subject's second PI containing regimen and must not contain any other PIs. - Subject is at least 18 years of age. - Subject has not been treated for an active opportunistic infection within 30 days of screening. Exclusion: - Subject has a history of active substance abuse or psychiatric illness that could preclude compliance to the protocol. - Female subject pregnant or lactating. - Use of an Investigational drug within 30 days prior to the initiation of drug dosing. - Subject is receiving systemic chemotherapy. - Subject has a history of acute or chronic pancreatitis.



Primary Contact:

Study Chair
Eugene Sun, M.D.
Divisional Vice President, Infectious Diseases and Virology Development

Backup Contact:


Location Contact:

Ft. Lauderdale, Florida 33316
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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