Expired Study
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Gilroy, California 95020


The purpose of this study is to compare overall survival in patients with previously-treated metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer treated with oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX4) and cetuximab with FOLFOX4 alone.


Inclusion Criteria: - Documented colorectal cancer which is EGFR-positive and is metastatic. - Prior irinotecan, alone or in combination, as first-line treatment of metastatic disease. Exclusion Criteria: - A serious uncontrolled medical disorder that, in the opinion of the Investigator, would impair the ability of the subject to receive protocol therapy. - Known dihydropyrimidine dehydrogenase (DPD) deficiency. - Known metastases in the central nervous system. - Symptomatic sensory or peripheral neuropathy. - More than one prior chemotherapy regimen for the treatment of metastatic colorectal cancer. - Prior oxaliplatin therapy. - Prior cetuximab or other therapy which targets the EGF pathway. - Prior chimerized or murine monoclonal antibody therapy.



Primary Contact:

Study Chair
E-mail: ClinicalTrials@ ImClone.com
ImClone LLC

Backup Contact:


Location Contact:

Gilroy, California 95020
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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