Expired Study
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St. Louis, Missouri 63110


RATIONALE: Imaging procedures, such as carbon-11 acetate positron emission tomography (PET) and fludeoxyglucose F 18 PET, may improve the ability to detect hepatocellular carcinoma (liver cancer) and allow doctors to plan the most effective treatment. PURPOSE: This clinical trial is studying how well carbon-11 acetate PET and fludeoxyglucose F 18 PET work in detecting cancer in patients with liver cancer.


INCLUSION: - Biopsy-proved HCC (stage I and II by conventional staging) or one or more of the following in a patient with clinically documented cirrhosis: - AFP > 200 mg/dL; - A contrast-enhancing tumor mass (>1 cm) by CT or MRI; or - A tumor mass confirmed by arteriography. - Patient must provide written informed consent and have completed conventional imaging and staging before initiation of PET imaging. EXCLUSION: - Pediatric patients under the age of 18 will be excluded from consideration from this study. - Patients with a known prior malignancy (with the exception of basal cell carcinoma of the skin and carcinoma in situ of the cervix) within 5 years will be excluded from entry into the study. However, patients with a prior HCC thought to have a new primary or recurrent HCC are eligible. - Pregnant and breastfeeding patients. - Patients with poorly controlled diabetes mellitus (fasting blood glucose level > 200 mg/dL)



Primary Contact:

Principal Investigator
William C. Chapman, M.D.
Washington University School of Medicine

Backup Contact:


Location Contact:

St. Louis, Missouri 63110
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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