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New York, New York 10011


The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.

Study summary:

This pilot study included 18 medical residents at two academic medical centers in New York City. All residents who participated in the study were assigned to work a night shift schedule for two weeks, and began the study on the morning prior to their first evening shift. The study subjects were randomly assigned to one of two groups: - Intervention diet -- consisting of 40% carbohydrates, 30% protein, and 30% fat with 2.4g of long chain fatty acid supplements (n=9) Total calories for males was 1600/day, and 1200/day for females - Control group -- ad lib diet. Main outcome measures included: - weight - resting metabolic rate - percent body fat - lipid profile - CRP - fasting glucose and insulin levels - urinary neurotransmitter levels - salivary cortisol - six cognitive tests of memory, attention, and executive function. Subjects were tested on day 1, 7, and 14 of the study.


Inclusion Criteria: - Medical resident in good standing at Cabrini Medical Center or Saint Vincent's Hospital, NY. - Must be scheduled for two consecutive weeks of night shift work. Exclusion Criteria: - Febrile illness - Smoker - Food allergies of any kind - Taking any prescription medication - History of diabetes or thyroid dysfunction - Body mass index (BMI)>30 - Pregnancy



Primary Contact:

Principal Investigator
Valerie A Jones, MD
Saint Vincent's Hospital, Manhattan

Backup Contact:


Location Contact:

New York, New York 10011
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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