Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Hartford, Connecticut 06106


Although widely used for the treatment of pediatric status asthmaticus, intravenous terbutaline has potentially significant side effects; may not improve outcomes; and may increase Intensive Care Unit (ICU) length of stay. This study is designed to test the efficacy of intravenous terbutaline for the treatment of status asthmaticus by adding intravenous terbutaline or placebo to standard asthma treatment. The dose of terbutaline or placebo will be titrated according to severity of illness as quantified by a validated clinical asthma score. Differences in outcomes between the study groups, such as length of stay, hospital costs, and lung function will be compared.


Inclusion Criteria: - Admission to the Connecticut Children's Medical Center (CCMC) Pediatric Intensive Care Unit (PICU) with a primary admission diagnosis of status asthmaticus - Modified Pulmonary Index Score (MPIS) of greater than or equal to 12 - Age between birth and 18 years old Exclusion Criteria: - Pre-existing cardiac or pulmonary disease - Existing respiratory failure (requiring invasive or non-invasive mechanical ventilation) - Hemodynamic or cardiovascular instability requiring inotropic support - The patient meets one of the criteria for withdrawal from the study due to patient safety concerns



Primary Contact:

Principal Investigator
Christopher Carroll, MD
CT Children's Medical Center

Backup Contact:


Location Contact:

Hartford, Connecticut 06106
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.