Expired Study
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Salt Lake City, Utah 84148


The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools, fruits). The treatment is also designed to be used as a search strategy in instances of word-finding difficulty. The study was devised to evaluate the extent to which treatment increases the ability to recall trained, as well as untrained, words.

Study summary:

The purpose of the proposed research is to examine the effects of a semantically-oriented treatment on word retrieval in persons with aphasia. The planned investigations are designed to further the development of semantic feature training so that it may serve as not only a mechanism for improving disrupted lexical semantic processing, but also as a compensatory strategy during word retrieval failures. The proposed research will also address the issue of exemplar typicality (Kiran & Thompson, 2003) by examining the effects of training typical versus atypical exemplars of various categories with individuals with different types of aphasia. A series of 24 single subject experimental designs will be conducted in the context of a group design to address the following experimental questions: - Will training atypical examples of living and artifact noun categories using semantic feature training result in a significantly different outcome* than training typical examples of living and artifact noun categories? - Will training of one category of nouns using semantic feature training result in improved retrieval of untrained categories of nouns? - Will effects of semantic feature training vary across aphasia types? - Will semantic feature training result in increased production of content during discourse? - Will generalization to untrained typical examples vary across generalization lists that are repeatedly exposed and those that are limited in exposure? (i.e., Does repeated exposure appear to contribute to generalization?) - Outcome measure will reflect acquisition, response generalization within category, and response generalization across category effects of treatment.


Inclusion Criteria: - Diagnosis of Wernicke's, Broca's, or Conduction aphasia with significant word-retrieval deficits - At least 6 months post-onset of single, left-hemisphere stroke - Minimum of high-school education - Visual and auditory acuity sufficient for experimental tasks - Nonverbal intelligence within normal limits Exclusion Criteria: - Diagnosed mental illness other than depression - Neurological condition other than that which resulted in aphasia - History of alcohol or substance abuse - Non-native English speaker - Premorbid history of speech/language disorder



Primary Contact:

Principal Investigator
Julie L. Wambaugh, PhD
VA Salt Lake City Health Care System, Salt Lake City

Backup Contact:


Location Contact:

Salt Lake City, Utah 84148
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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