Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Richmond, Virginia 23229


Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol. Under normal conditions, cortisol and other hormones are created by the body in response to physical and emotional stress, triggering a healthy stress response. People who suffer from psychotic major depression may have unusually high levels of cortisol circulating within them or abnormal patterns of cortisol levels, overloading the stress response mechanism and causing symptoms of psychosis such as delusional thoughts or hallucinations. If Corlux can keep the body's cortisol receptors from being overloaded, the stress response system may return to normal function, which may result in improvement of symptoms. The purpose of this 56 day study is to learn the safety and effectiveness of Corlux in patients who have been diagnosed with psychotic major depression (PMD).


Inclusion Criteria: Individuals eligible for enrollment into this study are male and female adult patients who: - Are 18 to 75 years of age - Have a diagnosis of major depressive disorder with psychotic features (DSM-IV 296.24 or 296.34) - Are able to provide written informed consent Exclusion Criteria: Individuals not eligible to be enrolled into the study are those who: - Have a major medical problem - Have previously participated in a Corlux (C-1073, mifepristone) clinical trial - Have a history of an allergic reaction to Corlux (C-1073, mifepristone)



Primary Contact:

Study Director
Katherine Beebe, PhD
Corcept Therapeutics

Backup Contact:


Location Contact:

Richmond, Virginia 23229
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.