Expired Study
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Cambridge, Massachusetts 02138


Purpose:

The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.


Study summary:

Muscle power, a separate physical attribute from strength, is an important determinate of physical functioning in the elderly, for example in avoiding impending falls, rising from a chair, and climbing stairs. Muscle power, which declines with aging at a different rate than strength, has been shown in previous studies to improve through power training utilizing specially designed exercise equipment. However, weighted vest exercise could provide an acceptable, low cost, readily accessible alternative. The hypotheses being tested in this study are: 1) weighted vest exercise will improve lower extremity power when compared to age matched controls in a standardized progressive resistance training program; 2) improvements in lower extremity power enhance functional performance as shown by improved gait velocity, stair climbing, and chair rise time; and 3) weighted vest exercise in impaired older adults will improve self-reported function and disability. One hundred sixty-four men and women ages 65 and older, with some physical limitation but able to climb stairs independently, will be randomized to one of two 16-week exercise programs. The intervention group will participate in a weighted vest exercise protocol, consisting of chair-based and stair-climbing exercise, while the control group will participate in a standardized progressive resistance training program. Participants in both programs will meet three times per week for 30-60 minutes per session, for a total of 16 weeks, at a research exercise gym, and will be under the direct supervision of research staff.


Criteria:

Inclusion Criteria: - Community dwelling men and women aged 65 or older - Ability to provide informed consent - Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time - Score of 24 or greater on the Folstein mini-mental status exam - Exhibit independent stair-climbing ability Exclusion Criteria: - Unstable acute or chronic disease - Neuromusculoskeletal impairment interfering with independent stair climbing - Abdominal aortic aneurysm - Exertional angina - History of ventricular arrhythmia - Inguinal or abdominal hernia - Symptomatic valvular heart disease


NCT ID:

NCT00158119


Primary Contact:

Principal Investigator
Jonathan F. Bean, MD, MS
Spaulding Cambridge Outpatient Center


Backup Contact:

N/A


Location Contact:

Cambridge, Massachusetts 02138
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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