Expired Study
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Minneapolis, Minnesota 55455


Purpose:

The purpose of this study is to determine if immunophilin ligands may have the potential to reverse hair loss.


Study summary:

Preliminary experiments in C57BL/6J mice showed that immunophilin ligand FK506 and its non-immunosuppressive analogs, GP11046 and GP11511 were capable of promoting telogen to anagen transition. Since GP11046 and GP11511 possess the neurotrophic properties of FK506 without its immunosuppressant capability, the neural action of these immunophilin ligands may play an important role in the hair cycle. This finding has significant clinical implications in that immunophilin ligands may have the potential to reverse alopecia. To further investigate this possibility we propose to explore the response of transplanted miniaturized scalp hair follicles to topically applied immunophilin ligands.


Criteria:

Inclusion Criteria: - Healthy men ages 18-65 with Hamilton type IV or V alopecia Exclusion Criteria: - Individuals who do not meet the inclusion criteria.


NCT ID:

NCT00177099


Primary Contact:

Principal Investigator
Marna Ericson, Ph D
University of Minnesota - Clinical and Translational Science Institute


Backup Contact:

N/A


Location Contact:

Minneapolis, Minnesota 55455
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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