Expired Study
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Pittsburgh, Pennsylvania 15232


The purpose of this study is to determine the complete response rate when CHOP-R chemotherapy in followed by Zevalin in previous untreated patients with follicular lymphoma

Study summary:

Patients with follicular lymphoma who require therapy and have been previously untreated are eligible for this non-randomized, phase II study evaluating up front therapy with CHOP-R x 3 cycles followed by zevalin and 4 additional weeks of rituxan.The complete response will be determined by combining IWC criteria and PET scanning.Secondary objectives include PET-CT conversion rate, frequency and severity of adverse events, duration of complete remission and time to next lymphoma therapy.


Inclusion Criteria: - Conformed diagnosis of follicular lymphoma, grades 1,2 or 3 - No prior chemotherapy - No prior monoclonal antibody therapy - Bulky or symptomatic disease, stage II-IV - Performance status 0-2 Exclusion Criteria: - Impaired bone marrow reserve - Presence of CNS lymphoma - Serious nonmalignant disease or active infection



Primary Contact:

Principal Investigator
Samuel A Jacobs, MD
University of Pittsburgh

Backup Contact:


Location Contact:

Pittsburgh, Pennsylvania 15232
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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