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Nashville, Tennessee 37212

  • Schizoaffective Disorder

Purpose:

Examines cognitive functioning in patients with schizophrenia or schizoaffective disorder who have been treated with antipsychotic medications. Patients will be assigned to take active medication (Buspar)or placebo along with their prescribed antipsychotic medication for six weeks. Patients' memory and problem-solving ability will be tested before and after medication.


Study summary:

Examines cognitive functioning in patients with schizophrenia or schizoaffective disorder who have been treated with olanzapine or risperidone for at least three months randomized to receive adjunctive treatment with a 5-HT1A agonist (buspirone, 15-30 mg/day)or placebo.


Criteria:

Inclusion Criteria: Subjects must meet all of the following criteria to be eligible for participation in the current research study. 1. Subjects will be males and females between 18-65 years of age; 2. Subjects will have a definite diagnosis by DSM-IV criteria for Schizophrenia or Schizoaffective Disorder; 3. The subjects or their legal guardian must sign the informed consent; 4. Subjects currently being treated with olanzapine or risperidone for a duration of at least 3 months Exclusion Criteria: 1. Subjects who are pregnant or lactating 2. Subjects who have brain damage and/or neurological disorders 3. Subjects who have current substance dependence 4. Subjects unable to provide informed consent


NCT ID:

NCT00178971


Primary Contact:

Principal Investigator
Herbert Y Meltzer, M.D.
Vanderbilt University Medical Center


Backup Contact:

N/A


Location Contact:

Nashville, Tennessee 37212
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: April 03, 2020

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