Expired Study
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Baltimore, Maryland 21224


Purpose:

The purpose of this study is to show that one form of mechanical airway clearance techniques, High Frequency Chest Wall Oscillation (HFCWO)using a pneumatic vest, will diminish exacerbations of COPD which will improve respiratory health status.


Study summary:

Approximately 60 to 70% of people with COPD have chronic cough and phlegm, the cardinal symptoms of chronic bronchitis or chronic mucus hypersecretion (CMH). Once thought to be a relatively benign condition, recent evidence shows that CMH in patients with established COPD is associated with greater decline in lung function, more frequent respiratory infections, more frequent exacerbations and increased mortality.Using mechanical airway clearance techniques (The Vest) will diminish exacerbations of COPD which will improve respiratory health status. Comparison: Patients randomly assigned to the vest will have fewer exacerbations of COPD,better quality of life and less health care use compared to patients assigned to a sham vest.


Criteria:

Inclusion Criteria: - Physician Diagnosis of COPD,chronic bronchitis and/or emphysema - FEV1/FVC < or = 70% - FEV1 < or = 65% - Current or former smoker > or = 20 pack years - History of 1 or more COPD exacerbations in past 6 months necessitation hospitalization, ED vist, antibiotic or steroid prescription Exclusion Criteria: - Other lung diseases - Co-morbid illnesses such as cancer, liver disease, cardiomyopathy - Recent chest wall or abdominal trauma or surgery that would preclude using the vest


NCT ID:

NCT00181207


Primary Contact:

Principal Investigator
Gregory B Diette, M.D.,M.H.S
Johns Hopkins Medicine


Backup Contact:

N/A


Location Contact:

Baltimore, Maryland 21224
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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