Expired Study
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Stanford, California 94305


To combine oxaliplatin and taxotere in patients who have had prior cisplatin therapy in bladder cancer.

Study summary:

To test the combination of oxaliplatin chemotherapy in combination with taxotere chemotherapy in patients with advanced bladder cancer who have failed one prior chemotherapy.


- Patient Population Type: Advanced Muscle Invasive Bladder Cancer - Prior Therapy: One prior therapy for advanced disease - Disease: Measurable disease - ECOG Performance: 0,1 - Indication: Histologically Proven Carcinoma of the bladder - For female patient of childbearing potential, neither pregnant nor breastfeeding, and under active contraception - Allergies: No known allergy to one of the study drugs - Patient Status: - No CNS metastases - No peripheral neuropathy > grade1 - No other serious concomitant illness - Fully recovered from any prior therapy - Informed Consent: Patient and doctor have signed informed consent - Lower Age Limit: Lower age limit >18 - Upper Age Limit: Upper Age Limit <70 - ANC: ANC >1500/mm3 or WBC > 3000/mm3 - Platelets: Platelets >100,000/mm3 - Creatinine: Creatinine <1.8mg/dL - Bilirubin: Bilirubin <=2.0 x ULN - SGPT: SGPT (ALT) <=1.5 x ULN (<4xULN if liver metastases present) - RBC: Hemoglobin > 9.0g/dL - Cardiovascular: No active congestive heart failure, no uncontrolled angina, no myocardial infarction within the past 6 months - Patients with metastatic cancer of the urothelial tract (TCC, Adenocarcinoma) - No prior exposure to Oxaliplatin - No cytotoxics or radiation 4 weeks prior to enrolling on protocol - PT/PTT normal



Primary Contact:

Principal Investigator
Dr. Sandy Srinivas
Stanford University

Backup Contact:


Location Contact:

Stanford, California 94305
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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