Stanford, California 94305

  • Prostate Cancer

Purpose:

The purpose of this study is to evaluate time to progression (TTP) by PSA in patients with high risk prostate cancer after definitive therapy.


Criteria:

Inclusion Criteria: - Patients who have undergone a radical prostatectomy (should have unmeasurable PSA) or radiation therapy for prostate cancer and who have high risk disease as defined by one of the following: - Node positive disease post-operatively - Capsule involvement - Seminal Vesicles involvement - Gleason score ≥ 8 - >50% of core biopsies that are positive - Clinical Stage T2c and T3 - Pre-op PSA > 15 plus Gleason score of 7 - Age greater than 18 - ECOG Performance Status 0-1 - Serum creatinine <= 1.5 mg/dl - Granulocyte count >= 1500/m3, Hemoglobin > 8.0 g/dl, and platelet count >= 100,000/m3 - Total bilirubin <= ULN - AST, ALT and Alkaline Phosphatase must be within the range allowing for eligibility. - Signed patient informed consent. - Men of childbearing potential must be willing to consent to using effective contraception while on treatment and for three months thereafter. Exclusion Criteria: - Peripheral neuropathy > grade 1 - History of severe hypersensitivity to Taxotere® or other drugs formulated with polysorbate 80. - Patients who have received previous chemotherapy or are being treated on another clinical trial using an investigational agent. - Active infection within 14 days of beginning treatment - Patients with a serious illness or medical condition, history of significant neurologic or psychiatric or active infection. - Patients with a current malignancy. Patients with prior a history of in situ lobular carcinoma of the breast, basal or squamous cell skin cancer, are eligible.


NCT ID:

NCT00186420


Primary Contact:

Principal Investigator
Sandy Srinivas, MD
Stanford University


Backup Contact:

N/A


Location Contact:

Stanford, California 94305
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: April 03, 2020

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