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Nashville, Tennessee 37023


Purpose:

In this trial we will evaluate and compare the efficacy and toxicity of oral topotecan with intravenous docetaxel in the second-line treatment of patients with non-small cell lung cancer.


Study summary:

Upon determination of eligibility, patients will be randomly assigned to one of two treatment arms: - Topotecan - Docetaxel For ever 2 patients treated, 1 will receive treatment A (Topotecan) and 1 will receive treatment B (Docetaxel). The study is not blinded so both the patient and the doctor will know which treatment has been assigned.


Criteria:

Inclusion Criteria: To be included in this study, you must meet the following criteria: - Relapsed or Progressive Disease - Stage IIIB (not candidate for combined modality) or IV - No more than one prior chemotherapy regimen - Able to perform activities of daily living without assistance - Measurable disease outside of radiation port - Adequate bone marrow, liver and kidney function - Must understand study and sign informed consent prior to enrollment Exclusion Criteria: You cannot participate in this study if any of the following apply to you: - Prior treatment with Topotecan or Docetaxel - Uncontrolled brain metastases - Moderate peripheral neuropathy Please note: There are additional inclusion/exclusion criteria. The study center will determine if you meet all of the criteria. If you do not qualify for the trial, study personnel will explain the reasons. If you do qualify, study personnel will explain the trial in detail and answer any questions you may have.


NCT ID:

NCT00193245


Primary Contact:

Principal Investigator
Howard A. Burris, MD
Sarah Cannon Research Institute


Backup Contact:

N/A


Location Contact:

Nashville, Tennessee 37023
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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