Expired Study
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Columbus, Ohio 43210


Purpose:

The purpose of this trial is to evaluate time to progression in women with hormone responsive advanced breast cancer treated with a combination of exemestane and fulvestrant.


Criteria:

Inclusion Criteria: - Proven breast cancer - Metastatic or locally advanced breast cancer - Hormonally responsive disease defined as estrogen (ER) and/ or progesterone receptor (PR) positive (>10% staining by immunohistochemistry) - Postmenopausal status - No more than 1 prior chemotherapy for stage IV metastatic breast cancer allowed - ECOG (Eastern Cooperative Oncology Group) performance status 0-2 - Adequate organ function - Exclusion Criteria: - No prior Exemestane or Fulvestrant - Uncontrolled intercurrent illness including but not limited to: - ongoing or active infection - symptomatic congestive heart failure - unstable angina pectoris - cardiac arrhythmia - myocardial infarction within the last 3 months - psychiatric illness/social situations that would limit compliance with study - Lymphangitic pulmonary disease; carcinomatous meningitis, bone marrow only metastases; and a rising tumor marker without any other site of metastatic disease. - Presence of bleeding diathesis or coagulopathy, patients requiring coumadin


NCT ID:

NCT00201864


Primary Contact:

Principal Investigator
Ewa Mrozek, MD
Ohio State University


Backup Contact:

N/A


Location Contact:

Columbus, Ohio 43210
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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