Expired Study
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Irvine, California 92612


Lasers are the treatment modality of choice for Port Wine Stain birthmarks.The epidermis is not totally spared due to partial absorption of energy therein by melanin that presents an optical barrier through which the light must pass to reach the underlying blood vessels. Absorption of laser energy by melanin causes localized heating in the epidermis, which may, if not controlled, produce permanent complications such as hypertrophic scarring or dyspigmentation.

Study summary:

The researchers want to establish a correlation between non-invasive skin temperature measurements and the minimum laser energy during skin laser treatment using cryogen spray cooling. This study would eliminate the need for test pulses to estimate the safe and acceptable radiant exposure prior to laser treatment.


Inclusion Criteria: - 7 years of age and older with diagnosis of port wine stain birthmark - 18 years of age and older with no port wine stain - non-pregnant women - apparent good health Exclusion Criteria: - age less than 7 years old - pregnant women - history of photodermatoses or skin cancer - current use of photosensitizing drugs



Primary Contact:

Principal Investigator
John S. Nelson, M.D., Ph.D
Beckman Laser Institute University of California Irvine

Backup Contact:


Location Contact:

Irvine, California 92612
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

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