New Haven, Connecticut 06519


We aim to study the efficacy of intravenous ceftriaxone in a four-week, inpatient, placebo-controlled, double-blind study, as an augmentation therapy in patients with bipolar disorder, currently depressed, who have failed to respond to conventional treatments.


Inclusion Criteria: - DSM-IV diagnosis of bipolar disorder - Presence of a current major depressive episode on the SCID - Score of 17 or greater on the HDRS - Failure to respond to two previous medication trials - Capable of giving voluntary written consent Exclusion Criteria: - Hypersensitivity to penicillin or cephalosporin, resulting in anaphylaxis - Significant current substance dependence/abuse within 3 months preceding the trial - Significant history of intravenous drug abuse - Active suicidal ideation - Pregnant/lactating mothers - Significant medical history - Patients on anticoagulation treatment - Patients who test positive for HIV or Hep B or C



Primary Contact:

Principal Investigator
Zubin Bhagwagar, MD PhD
Yale University

Kathleen Maloney, BA
Phone: 203-974-7496

Backup Contact:


Location Contact:

New Haven, Connecticut 06519
United States

There is no listed contact information for this specific location.

Site Status: Recruiting

Data Source:

Date Processed: February 04, 2019

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