Expired Study
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Minneapolis, Minnesota 55417


The present study is designed to find out if N-acetylcysteine works in reducing alcohol drinking and craving.

Study summary:

The 2 groups (placebo and N-acetylcysteine) will be compared in a double-blind, placebo-controlled trial. The total study duration is 9 weeks which includes a 1-week screening period and an 8-week randomized study drug treatment period.


Inclusion Criteria: - age 18 - 65 - alcohol dependence by DSM-IV - heavy drinking at least 4 times in the past month - able to provide informed consent Exclusion Criteria: - current drug abuse or dependence by DSM-IV criteria (except nicotine or cannabis) - current psychotic disorders, bipolar disorders, or cognitive disorders - current suicidal or homicidal ideation - positive illicit drug screen (except cannabis) - Clinical Institute Withdrawal Assessment for Alcohol, Revised >15 - initiation of individual therapy or counseling in the past 3 months - changes in doses of psychiatric medications in the past 3 months - clinically unstable cardiac, hepatic, renal, neurologic, or pulmonary disease - current use of naltrexone, disulfiram or acamprosate - pregnant or nursing women, or inadequate birth control methods in women of childbearing potential



Primary Contact:

Principal Investigator
Gihyun Yoon, MD
Minneapolis Veterans Affairs Medical Center

Backup Contact:


Location Contact:

Minneapolis, Minnesota 55417
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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