Expired Study
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New York, New York 10029


Purpose:

The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients. This study will examine if the switching from one pain medication to another can be done over a 24 hour period. Oxymorhone, the drug being studied, is an FDA approved drug for treatment of severe pain.


Criteria:

Inclusion Criteria: - Age of 18 to no upper limit - Chronic pain of nociceptive, neuropathic, or mixed origin - Patients with chronic non cancer pain - Ongoing chronic opioid treatment with either oral morphine or oxycodone (long term - more than 3 months of at least a total daily opioid dose of 60 mg morphine or of 30 mg oxycodone) - Pain of moderate intensity (>4, on the numerical scale 0-10) despite ongoing opioid therapy> - Non-pregnant, non-lactating women - Sufficient language skills to communicate with research staff Exclusion Criteria:Non-ambulatory patients - Clinically significant respiratory, renal, hepatic, or cardiac disease. - Documented diagnosis of sleep apnea (the study physician may exclude patients who present with clinical features and complaints suggestive of a diagnosis of probable sleep apnea) - History of illicit drug or alcohol dependence or abuse, abnormal drug taking / seeking behaviors - Severe depression (> 26 on the BDI) - Patients who exhibit a score on the Mini Mental Status Exam (MMSE) of 26 or less. (The range of scores for mild dementia is 21-26 on the MMSE). - Workman compensation, current or pending medical-legal litigation - Hypersensitivity to study medication (oxymorphone)


NCT ID:

NCT00580294


Primary Contact:

Principal Investigator
Marco Pappagallo, MD
Mount Sinai School of Medcine


Backup Contact:

N/A


Location Contact:

New York, New York 10029
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: June 25, 2018

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