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Rochester, Minnesota 55905


Randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy. Hypothesis is that clonidine will be as effective as steroid for this condition.


Inclusion Criteria: - Residents 18 years or older of Olmsted or contiguous counties and identified as having an acute unilateral radicular syndrome of less than 3 months duration (leg pain>back, discogenic cause, one or more of the following: - Positive SLR - Myotomal weakness - Dermatomal sensory loss) and with concordant - Confirmatory findings on recent MRI or CT myelogram Exclusion Criteria: - History of recent spinal trauma - Cauda equina syndrome - Progressive neurological deficit - Motor deficit - Pathological or infectious etiology - Involvement in workers' compensation claim - History of adverse reaction to corticosteroids, local anesthetic or clonidine - History of one or more corticosteroid injection(s) (equivalent to 40 mg of triamcinolone acetate) in the preceding 4 months - Pregnant; OR - Severe medical disease



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Rochester, Minnesota 55905
United States

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Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

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