Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

West Haven, Connecticut 06516


This study investigates the interactions between NMDA (N-Methyl-D-aspartic acid) antagonism and GABA (gamma-aminobutyric acid) system as it relates to cognitive function assessed by ERPs (event-related potentials) in healthy volunteers.


Inclusion criteria: - Ages of 21-45 years from all ethnic backgrounds. - Male or female. - Written informed consent. Exclusion criteria: - DSM-IV diagnosis for a psychotic, depressive or anxiety disorder. - A history of significant medical/neurological disease such as cardiac, thyroid, renal, hepatic abnormality, seizure disorder. Unstable medical condition based on EKG, vital signs, physical examination and laboratory work-up (CBC with differential, SMA-7, LFTs, TFTs, UA, Utox). - History of abnormal EEG. - History of severe allergies or multiple adverse drug reactions. - Any medication that could interfere with either the safety of the study and/or the outcome measures. - Any other conditions which in the opinion of the investigator would preclude participation in the study. - History of major psychiatric disorder in first degree relatives. - Current substance abuse/dependency determined by urine toxicology. - Treatment with medications with CNS effects. - Treatment with benzodiazepines within one week prior to testing. - Current treatment with medications with psychotropic effects. - Education < 10th grade. - IQ < 70, MR. - Non-English speaking.



Primary Contact:

Principal Investigator
Mohini Ranganathan, M.D.
Yale School of Medicine, Associate Professor

Backup Contact:


Location Contact:

West Haven, Connecticut 06516
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.