Expired Study
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Lone Tree, Colorado 80124


Purpose:

This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the determination of the absence of endometrial expression of the integrin, alpha v, beta 3 vitronectin. This is a prospective randomized trial in which all patients will undergo endometrial biopsy prior to initiation of ovarian stimulation for in vitro fertilization and then undergo randomization to a three month course of a depot preparation of the GnRH agonist leuprolide acetate in depot suspension prior to ovarian stimulation or standard therapy. prio


Study summary:

See summary


Criteria:

Inclusion Criteria: - Infertility - Surgical diagnosis of endometriosis - Normal ovarian reserve testing - Regular menses Exclusion Criteria: - Irregular menses - Undiagnosed abnormal uterine bleeding - Pregnancy - Prior adverse reaction to any GnRH agonist - Ovarian cystic or solid mass > 3cm in mean diameter at study entry - Use of a depot preparation of a GnRh agonist or any hormonal therapy for endometriosis within 6 months of study entry - Current hepatic, renal, hematologic or psychiatric disorder


NCT ID:

NCT00621179


Primary Contact:

Principal Investigator
Eric S Surrey, M.D.
Colorado Center for Reproductive Medicine


Backup Contact:

N/A


Location Contact:

Lone Tree, Colorado 80124
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: June 25, 2018

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