Expired Study
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Houston, Texas 77030


The study is designed to compare the effects of nebivolol (10, 20, 40mg/day) with another beta blocker, extended-release metoprolol, at a range of doses. Its purpose is to study the mechanism of action of nebivolol on forearm blood flow, nitric oxide availability and other biomarkers.


Inclusion Criteria: - Male or female, ambulatory outpatients 18-79 years old at screening - Minimum 2-year history of Stage I/II hypertension - Qualifying blood pressure criteria for study entry and for randomization - Willing to adhere to the dietary compliance and undergo protocol procedures - Have a lifestyle that will permit him/her to attend all evaluations, including those conducted on consecutive days Exclusion Criteria: - Have any form of secondary hypertension - Have clinically significant respiratory or cardiovascular disease - Presence/history of coronary artery disease or peripheral vascular disease - Have diabetes mellitus, Type I or II - Have a history of hypersensitivity to nebivolol, metoprolol, or any beta-blocker



Primary Contact:

Study Director
Tatjana Lukic, MD., M.Sc.
Forest Research Institute, Inc., a Subsidiary of Forest Laboratories, Inc.

Backup Contact:


Location Contact:

Houston, Texas 77030
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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