Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Zanesville, Ohio


This study will compare the safety and efficacy of once daily dosing of aliskiren to twice daily dosing of aliskiren in patients with moderate hypertension


Inclusion Criteria: - Have diagnosis of uncomplicated essential hypertension; newly diagnosed or who have not received antihypertension medication within 4 weeks of visit 1 must have an office cuff mean sitting Diastolic Blood pressure (msDBP) > 100 mmHg and < 110 mmHg at visit 1. If patient is receiving antihypertensive treatment, must have a cuff msDBP > 95 mmHg and < 110 mmHg at visit 1 - Prior to randomization, all patients must have an office cuff msDBP >or= 100 mmHg and <or = 110 mmHg. Exclusion Criteria: - Participation in another aliskiren trial or previous treatment with aliskiren during last 6 months and who qualified to be randomized or enrolled into the active drug treatment period - Pregnant or nursing women - Women of child bearing potential unwilling to use protocol specific contraceptive methods - Office cuff blood pressure of msDBP ≥ 112 mmHg and/or mean sitting Systolic Blood Pressure (msSBP) ≥ 200 mmHg). - Secondary form of hypertension - History of heart failure New York Heart Association (NYHA Class II, III and IV) - Previous history of hypertensive encephalopathy or stroke, transient ischemic attack (TIA), heart attack, coronary bypass surgery or any percutaneous coronary intervention (PCI) - Elevated Serum potassium (> or = 5.3 mEq/L (mmol/L) at Visit 1 - Type 1 or Type 2 diabetes mellitus not well controlled - Other protocol-defined inclusion/exclusion criteria may apply



Primary Contact:

Principal Investigator

Backup Contact:


Location Contact:

Zanesville, Ohio
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.