Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Nashville, Tennessee 37240


The purpose of this study is to compare the effectiveness of ondansetron, metoclopramide, and promethazine for the treatment of nausea in the adult emergency department population. We hypothesize that a single intravenous dose of ondansetron is more effective in reducing nausea than a single IV dose of metoclopramide, promethazine or normal saline placebo in undifferentiated adult emergency department patients.


Inclusion Criteria: - All patients age 18 or older who present to the ED with a complaint requiring antiemetic treatment who do not meet the exclusion criteria. Exclusion Criteria: - Patients less than 18 years of age - Unstable patients with SBP < 90 - Patients with a stated or documented allergy to any of the study medications - Patients whose nausea rating if < 40 on the pretreatment VAS scale - Patients who have received a commonly accepted antiemetic within the previous 24 hours - Patients unwilling or unable to complete the assessment tool before and 30 minutes after study drug dosing



Primary Contact:

Principal Investigator
Tyler W Barrett, MD
Vanderbilt University

Backup Contact:


Location Contact:

Nashville, Tennessee 37240
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.