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Galveston, Texas 77555


This study will assess the potential interaction and subjective effects between intravenous cocaine and SYN117 in non-treatment seeking cocaine dependant subjects


Inclusion Criteria: - non treatment seeking cocaine dependent - English speaking - meet DSM IV TR criteria for cocaine dependence - pulse 50-90bpm - systolic BP 85-140 mmHg - diastolic BP 45-90 mmHg - essentially normal liver and kidney function blood tests - ECG normal - sign informed consent - negative urine pregnancy test at screening and admission Exclusion Criteria: - history or evidence of seizure disorder or brain injury - previous medically adverse reaction to cocaine, including loss of consciousness, chest pain or epileptic seizure - neurological disorders, organic brain disease, dementia - psychiatric disorders such as psychosis, schizophrenia, bipolar disorder, major depression - history of suicide attempts within past 3 months or suicidal ideation/plan - history of clinically significant heart disease or hypertension - family history in 1st degree relatives of early cardiovascular morbidity or mortality - untreated or unstable medical conditions - positive HIV test - pregnant or nursing - have asthma or are currently using alpha, beta agonists or theophylline or other sympathomimetics - test positive for other drugs of abuse with the exception of cocaine, cocaine metabolites or marijuana - any other illness, condition or use of psychotropic medications which preclude safe/successful completion of the study - currently on parole



Primary Contact:

Study Chair
Stephen Bandak, MD
Biotie Therapies Inc.

Backup Contact:


Location Contact:

Galveston, Texas 77555
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

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