Expired Study
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Salt Lake City, Utah


The primary aim of this study is to investigate if AZD1386 can relieve the pain induced by the surgical removal of one lower wisdom-tooth. This will be done by comparing the effect of AZD1386 to placebo ("inactive substance") on pain. A number of patients will instead receive the common painkiller naproxen for comparison purposes. Rescue medication, acetaminophen, will be allowed if a need for additional painkillers would arise. A number of patients will receive naproxen as control.


Inclusion Criteria: - Patients scheduled for surgical removal of one partial or complete impacted mandibular third molar. - Provision of signed informed consent. Exclusion Criteria: - History of somatic disease/condition, which may interfere with the objectives for the study, as judged by the investigator. - Clinically significant illness or clinically relevant trauma within the 2 weeks prior to the administration of the investigational product, as judged by the investigator. - A family history of short QT syndrome (SQTS) or sudden cardiac death (SCD) amongst first degree relatives - Patients with a body temperature >37.5°C at Visit 2, before start of surgical procedures



Primary Contact:

Principal Investigator
Lynn Webster, MD
Lifetree Clinical Research3838 South, 700 East, Suite 202Salt Lake City, Utah 84106, USA

Backup Contact:


Location Contact:

Salt Lake City, Utah
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

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