Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Rochester, Minnesota 55905


Purpose:

RATIONALE: Gathering information about allergies to metals may help doctors learn whether having an allergy to metal used in dental work increases the risk of developing oral cancer. PURPOSE: This clinical trial is studying contact allergies to dental metal as a possible risk factor for oral cancer.


Study summary:

OBJECTIVES: - Identify the relationship between intraoral metal contact allergy and epithelial carcinogenesis in patients with newly or previously diagnosed intraoral squamous cell carcinoma. - Compare the prevalence of metal contact allergy in these patients with control data from other existing study populations. OUTLINE: This is a multicenter study. - Participants undergo metal patch testing using 27 metals* commonly used in dental repairs that are part of the Mayo metal series. Metal patches are applied to the patient's back for 3 days and the back is read on days 3 and 5. Relevant patient data obtained from their medical and dental history, physical exam, laboratory values and treatment are documented. NOTE: *Healthy volunteers (control) undergo metal patch testing using 8 metals most commonly positive for contact allergens.


Criteria:

DISEASE CHARACTERISTICS: - Meets 1 of the following criteria: - Newly or previously diagnosed oral squamous cell carcinoma - Recruited from the otorhinolaryngology departments of Mayo Clinic Rochester and Mayo Clinic Arizona - Healthy volunteer (control) - No history of intraoral squamous cell carcinoma - Employed at Mayo Clinic Rochester or Mayo Clinic Arizona PATIENT CHARACTERISTICS: - No immunosuppression - No other conditions that interfere with patch testing PRIOR CONCURRENT THERAPY: - Not specified


NCT ID:

NCT00693550


Primary Contact:

Study Chair
James A. Yiannias, MD
Mayo Clinic


Backup Contact:

N/A


Location Contact:

Rochester, Minnesota 55905
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.