Expired Study
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Kansas City, Missouri 64108


The purpose of this study is to compare the cardiovascular risks of growth hormone deficient young adult males who have completed growth hormone therapy to healthy young adult males.

Study summary:

Adults with growth hormone deficiency are at risk for cardiovascular disease. What age this begins is not known. The objectives of this study are to compare the following measurements between growth hormone deficient young males 3-7 years post completion of growth hormone treatment and age related healthy controls: 1. Carotid artery imaging 2. Metabolic and cardiac parameters 3. Body composition measurements


Growth Hormone Deficient Inclusion Criteria: - Males, 18-25 years old - Completed growth hormone therapy approximately 3-5 years prior to study enrollment - History of multiple pituitary hormone deficiencies or growth hormone stimulation test <7 at initiation of growth hormone therapy Healthy Control Inclusion Criteria: - Males, 18-25 years old - No confirmed endocrine diagnosis including Diabetes and thyroid disorders - BMI - z-score within 2 SD of mean Exclusion Criteria: - Known risk factors for cardiovascular disease (eg tobacco use, hypertension, diabetes) - Family history of early cardiovascular disease (myocardial infarction or stroke <55years of age) in first degree family members - Any implanted device - Medication known to interfere with glucose or lipid metabolism or to influence blood pressure - Chronic organ illness (eg severe asthma, hepatic or nephritic conditions)



Primary Contact:

Principal Investigator
Carol Huseman, MD
Children's Mercy Hospital Kansas City

Backup Contact:


Location Contact:

Kansas City, Missouri 64108
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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