Expired Study
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Cincinnati, Ohio 45267


Purpose:

Feasibility trial to evaluate recovery and survival of red blood cells (RBCs) from Mirasol-treated whole blood


Study summary:

Radiolabeling of red blood cells (RBCs) followed by infusion back to the donor is commonly used to test the quality of RBCs in a person. By measuring the level of radioisotope in a blood sample, these tests evaluate what percentage of the RBCs remain in the bloodstream after 24 hours (recovery) and can predict how long the RBCs will remain in circulation (survival). The IMPROVE trial is a feasibility trial to evaluate these parameters in RBCs obtained from whole blood units that have been treated with the Mirasol System.


Criteria:

Inclusion Criteria: - healthy adults who meet AABB (formerly known as the American Association of Blood Banks) criteria for whole blood donation - females incapable of becoming pregnant - males agreeing to use contraception during trial Exclusion Criteria: - pregnancy or nursing - abnormal medical history (bleeding disorders, anemia, myocardial ischemia, uncontrolled hypertension, heart disease, epilepsy) - major surgery - use of drugs affecting coagulation or RBC function - recent participation in other trials which may confound results


NCT ID:

NCT00742001


Primary Contact:

Principal Investigator
Jose Cancelas-Perez, M.D, Ph.D
University of Cincinnati, Hoxworth Blood Center


Backup Contact:

N/A


Location Contact:

Cincinnati, Ohio 45267
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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