Expired Study
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Santa Ana, California


Purpose:

The purpose of this study is to determine the effect of JTT-302 on the increase of High Density Lipoprotein-Cholesterol (HDL-C) levels when administered daily for four weeks in subjects with low HDL-C levels.


Criteria:

Inclusion Criteria: - Subjects with a Body Mass Index (BMI)≤ 35 kg/m2 - Subjects with the following lipid parameters at Visit 1 (screening visit) and Visit 3 (diet stabilization period): - HDL-C ≤ 40 mg/dL (Men) and ≤ 50 mg/dL (Women) - TG ≤ 500 mg/dL - LDL-C ≤ 190 mg/dL - Subjects who are generally healthy as determined by pre-study medical history, physical examination, vital signs and 12-lead ECG Exclusion Criteria: - Females who are pregnant or breast-feeding - AST, ALT or total bilirubin ≥ 2.0 x ULN at Visit 1 (screening visit) or Visit 3 (diet stabilization period) - Serum thyroid stimulating hormone (TSH) and levothyroxine (T4) outside of the central laboratory reference range at the screening visit - Medical history of diabetes mellitus or two fasting serum glucose measurements > 126 mg/dL at the screening visit - Subjects with hypertension, or two blood pressure measurements ≥ 140 mm Hg systolic or ≥ 90 mm Hg diastolic at the screening visit - History of drug or alcohol abuse within 12 months of the screening visit - Use of medications defined in the protocol within six-weeks prior to the screening visit and throughout the study - Use of Cytochrome P450 3A4 inducers or inhibitors, as defined in the protocol within four weeks of the screening visit and throughout the study


NCT ID:

NCT00749788


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

Santa Ana, California
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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