Expired Study
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Boston, Massachusetts 02115


Purpose:

The purpose of this study is to determine whether reducing inflammation in blood vessels with an aspirin-like drug called salsalate will improve blood vessel function.


Study summary:

To test the hypothesis that inhibition of I [kappa] B kinase [beta] (IĸKβ), an inflammatory mediator, by high dose salsalate, will restore insulin-mediated endothelium-dependent vasodilation in subjects with atherosclerosis.


Criteria:

Inclusion Criteria: - Non-smoking adult subjects with known atherosclerosis Exclusion Criteria: - Uncontrolled hypertension (> 140/90 mmHg) - Untreated hypercholesterolemia (LDL > 160 mg/dL) - Diabetes mellitus - ALT > 150 - Creatinine > 1.4 mg/dL - Concommitant use of warfarin


NCT ID:

NCT00760019


Primary Contact:

Principal Investigator
Joshua A. Beckman, M.D.
Brigham and Women's Hospital


Backup Contact:

N/A


Location Contact:

Boston, Massachusetts 02115
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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